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[Retracted] MCM6 Promotes Hepatocellular Carcinoma Progression via the Notch Pathway: Clinical, Functional, and Genomic Insights

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成果类型:
期刊论文
作者:
Hou, Liangjuan;Zeng, Xin;Li, Xuan;Zhao, Chune;Zou, Juan;...
通讯作者:
Liu, Gang(liugangscience@163.com)
作者机构:
[Hou, Liangjuan; Zeng, Xin] Department of Histology and Embryology, Chongqing Three Gorges Medical College, Wanzhou, Chongqing
404120, China
[Li, Xuan] Department of Embryo Laboratory, Changsha Reproductive Medical Hospital, Hunan, Changsha
410000, China
[Zhao, Chune; Liu, Gang] Department of Infectious Disease, Three Gorges Hospital of Chongqing University, Chongqing University, Wanzhou, Chongqing
通讯机构:
[Chune Zhao; Xuan Li; Liangjuan Hou; Gang Liu; Xin Zeng] D
[Juan Zou; Yukun Li] H
Department of Infectious Disease,Three Gorges Hospital of Chongqing University,Chongqing University,China<&wdkj&>Department of Embryo Laboratory,Changsha Reproductive Medical Hospital,Changsha,China<&wdkj&>Department of Histology and Embryology,Chongqing Three Gorges Medical College,Wanzhou,China<&wdkj&>Hunan Province Key Laboratory of Tumor Cellular & Molecular Pathology,Cancer Research Institute,University of South China,China
语种:
英文
关键词:
Introduction;Materials and Methods;Results;Discussion;Conclusion;Abstract;Data Availability;Additional Points;Ethical Approval;Consent;Disclosure;Conflicts of Interests;Authors’ Contributions;Funding Statement;Acknowledgements;Acknowledgments;Supplementary Materials;Reference;Dataset Description;Dataset Files;Abstract;Introduction;Introduction and Materials;Introduction and Methods;Materials;Materials and Methods;Methods;Results;Discussion;Results and Discussion;Discussion and Conclusion;Results and Conclusion;Conclusion;Conclusions;Data Availability;Additional Points;Ethical Approval;Consent;Disclosure;Conflicts of Interest;Authors’ Contributions;Funding Statement;Acknowledgements;Supplementary Materials;References;Appendix;Abbreviations;Preliminaries;Introduction and Preliminaries;Notation;Proof of Theorem;Proofs;Analysis of Results;Examples;Numerical Example;Applications;Numerical Simulation;Model;Model Formulation;Systematic Palaeontology;Nomenclatural Acts;Taxonomic Implications;Experimental;Synthesis;Overview;Characterization;Background;Experimental;Theories;Calculations;Model Verification;Model Implementation;Geographic location;Study Area;Geological setting;Data Collection;Field Testing;Data and Sampling;Dataset;Literature Review;Related Works;Related Work;System Model;Methods and Data;Experimental Results;Results and Analysis;Evaluation;Implementation;Case Presentation;Case Report;Search Terms;Case Description;Case Series;Background;Limitations;Additional Points;Case;Case 1;Case 2 etc.;Concern Details;Retraction Details;Copyright;Related Articles
期刊:
Computational and Mathematical Methods in Medicine
ISSN:
1748-6718
年:
2022
卷:
2022
机构署名:
本校为第一机构
院系归属:
医学院
摘要:
Objective. To evaluate the expression profile of MCM6 in HCC and the relationship between MCM6 level and clinicopathological parameters through bioinformatics analysis of several databases. Methods. MCM expression level, clinical parameters, survival data, and gene set enrichment analysis were analyzed by bioinformatics database, including Oncomine™, UALCAN, HCCDB, TCGA, cBioPortal, and LinkedOmics. Real-time PCR, western blotting, and IHC staining were conducted to identify the expression of MCM6 in HCC compared to normal liver tissues. Resul...

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