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Nitrogen-doped carbon dots as a "turn-off" fluorescence probe for mercury(ii) detection and live cell imaging

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成果类型:
期刊论文
作者:
Lei, Yufei;Li, Qi;Li, Qian;He, Dongxiu;Xue, Jinhua;...
通讯作者:
Wang, Jikai;Xiao, XL
作者机构:
[Li, Qian; Wang, Jikai; Li, Qi; Lei, Yufei; Xiao, Xilin; Liao, Lifu; Xiao, XL; He, Dongxiu; Xue, Jinhua; Wang, JK] Univ South China, Sch Chem & Chem Engn, Sch Pharmaceut Sci Sch Publ Hlth, Sch Pharmaceut Sci,Sch Publ Hlth, Hengyang 421001, Hunan, Peoples R China.
[Xiao, Xilin; Xiao, XL] Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China.
通讯机构:
[Xiao, XL ; Wang, JK] U
Univ South China, Sch Chem & Chem Engn, Sch Pharmaceut Sci Sch Publ Hlth, Sch Pharmaceut Sci,Sch Publ Hlth, Hengyang 421001, Hunan, Peoples R China.
Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China.
语种:
英文
关键词:
Biocompatibility;Carbon;Cells;Cytology;Doping (additives);Fluorescence quenching;Medical imaging;Mercury compounds;Nitrogen;Probes;Carbon dots;Detection cells;Fluorescence probes;Gum arabic;Hydrothermal methods;Live-cell imaging;Mercury detection;Nitrogen-doped carbons;Synthesised;Turn offs;Fluorescence imaging;carbon;fluorescent dye;gum arabic;mercury;nitrogen;Article;cancer cell;controlled study;cytotoxicity;fluorescence imaging;human;human cell;in vitro study;limit of detection;live cell imaging;optics;particle size;quantitative analysis;synthesis;triple negative breast cancer;water solubility
期刊:
NEW JOURNAL OF CHEMISTRY
ISSN:
1144-0546
年:
2024
卷:
48
期:
14
页码:
6246-6253
基金类别:
This research was supported by the Hunan Provincial Natural Science Foundation of China (No. 2023JJ50139), and the Scientific Research Project of Hunan Provincial Health Commission (No. C202312067687).
机构署名:
本校为第一且通讯机构
院系归属:
化学化工学院
公共卫生学院
摘要:
In this paper, nitrogen-doped carbon dots (NCDs) were synthesized via a facile hydrothermal method using gum arabic (GA) and tris(hydroxymethyl)methyl aminomethane (tris) as precursors. The resultant NCDs show uniform size distribution and stable optical performance. Then a fluorescent signal quenching probe based on NCDs was proposed for the quantitative detection of mercury ions (Hg2+). The developed fluorescent nanoprobe based on NCDs demonstrated a good linear relationship in the range of 10 to 120 μM (R2 = 0.99265) for toxic mercury(ii), ...

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