Quartz crystal microbalance with β-cyclodextrin/TiO2 composite films coupled with chemometrics for the simultaneous determination of urinary 1- and 2-naphthol
A novel sensitive method was presented for the simultaneous determination of 1-naphthol (1-NAP) and 2-naphthol (2-NAP) in human urine samples. This method is based on the combination of the high sensitivity of quartz crystal microbalance (QCM) and excellent predictive ability of chemometrics. Nanocrystalline TiO2 films were used as substrates for immobilizing β-cyclodextrin (β-CD) onto the QCM surface. The sensing layer consisting of β-CD and nanocrystalline TiO2 particles was characterized by X-ray photoelectron spectroscopy (XPS), thermogravimetric analysis (TG) and IR spectro...
