Effect of the Pulsed Electromagnetic Field Treatment in a Rat Model of Senile Osteoporosis In Vivo

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成果类型：

期刊论文

作者：

Zhou, Jun;Wang, Jinling;Qu, Mengjian;Huang, Xiarong;Yin, Linwei;...

通讯作者：

Yahua Zeng

作者机构：

[Huang, Fujin; Ning, Pengyun; Zhou, Jun; Wang, Jinling; Liao, Yang; Zeng, Yahua; Zhong, Peirui; Huang, Xiarong; Yin, Linwei; Qu, Mengjian] Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Dept Rehabil,Rehabil Med Ctr,Rehabil Lab, Hengyang, Peoples R China.

[Zeng, Yahua] Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Dept Rehabil, Hengyang 421001, Hunan, Peoples R China.

通讯机构：

[Yahua Zeng] D

Department of Rehabilitation, Rehabilitation Medicine Center, Rehabilitation Laboratory, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, China

语种：

英文

关键词：

bone architecture;bone loss;osteoporosis;pulsed electromagnetic field;Wnt/β-catenin signaling

期刊：

Bioelectromagnetics

ISSN：

0197-8462

年：

2022

卷：

期：

页码：

438-447

DOI：

10.1002/bem.22423

基金类别：

The authors would like to thank Medjaden Bioscience for assisting in language editing of this manuscript. This study was supported in part by grants from the National Natural Science Fund of China (#81973917), Natural Science Foundation of Hunan (#2021JJ40493), Health Commission of Hunan (#202103060198 and #20200464), and The Key Project of South China University (#USCKF201902K02).

机构署名：

本校为第一机构

摘要：

This study assessed the effects of pulsed electromagnetic fields (PEMF) in a rat model of senile osteoporosis and the underlying molecular events. 24-month-old male Sprague–Dawley (SD) rats were randomly divided into control and PEMF groups (n = 8 per group) using a random digit table, while 3-month-old male SD rats were set as the young-age control group. Rats in the PEMF group were treated by PEMF for 40 min/day for 5 days/week. Bone mineral density/microarchitecture, level of serum bone-specific alkaline phosphatase (BALP), tartrate-resista...

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Effect of the Pulsed Electromagnetic Field Treatment in a Rat Model of Senile Osteoporosis In Vivo

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