The chemical speciations of uranium of a sandstone uranium deposit in the Yili Basin were quantitative analyzed using the method of sequential chemical extraction, and the implications of which for in-situ leaching of uranium were discussed. The proportion of chemical speciations of uranium shows that the bound to carbonates≥the bound to Fe-Mn oxides≥the exchangeable≥the residual≥the bound to sulfide-organic matter speciation, which is beneficial to cost reduction on in-situ leaching of uranium and environmental protection. The active urani...