OBJECTIVE To study the effect of niacin combined with curcumin on blood lipids and inflammatory factors expression in hyperlipidemic rats. METHODS Fifty SD rats were randomly divided into normal control group,model group,niacin group〔niacin 100 mg /( kg·d) 〕,curcumin group〔curcumin 100 mg /( kg·d) 〕and combination therapy group 〔Niacin 100 mg /( kg·d) + curcumin 200 mg /( kg·d) 〕. Detection of serum lipids after 8weeks. All the rats were killed and the liver samples were taken,expression of TNF-α and IL-6 in liver were detec...