This review summarizes four leading strategies used to promote the therapeutic effects of immunogenic cell death (ICD) via nanotechnology, including increasing the localized concentration of an ICD inducer in tumor, inducing various intracellular reactions, catalyzing the activity of antigen‐presenting cells, and protecting the function of cytotoxic T cells, together with an overview of the state‐of‐the‐art clinical applications of ICD via nanotechnology. Abstract Immunotherapy represents the most promising treatment strategy for cancer, bu...