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Promotion of ICD via Nanotechnology

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成果类型:
期刊论文
作者:
Qin, Yang;Zhang, Haitao;Li, Yunxian;Xie, Ting;Yan, Shuang;...
通讯作者:
Zifen Guo<&wdkj&>Hua Wei<&wdkj&>Cui-Yun Yu<&wdkj&>Zifen Guo Zifen Guo Zifen Guo<&wdkj&>Hua Wei Hua Wei Hua Wei<&wdkj&>Cui-Yun Yu Cui-Yun Yu Cui-Yun Yu
作者机构:
[Xie, Ting; Qu, Jun; Guo, Zifen; Wei, Hua; Zhang, Haitao; Qin, Yang; Li, Yunxian; Lv, Shaoyang; Ouyang, Feijun; Wang, Jiaqi; Yu, Cui-Yun; Yan, Shuang] Univ South China, Inst Pharm & Pharmacol, Hunan Prov Cooperat Innovat Ctr Mol Target New Dru, Sch Pharmaceut Sci,Hengyang Med Sch, Hengyang 421001, Peoples R China.
通讯机构:
[Zifen Guo; Hua Wei; Cui-Yun Yu; Zifen Guo Zifen Guo Zifen Guo; Hua Wei Hua Wei Hua Wei; Cui-Yun Yu Cui-Yun Yu Cui-Yun Yu] H
Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, Institute of Pharmacy & Pharmacology, School of Pharmaceutical Science, Hengyang Medical School, University of South China, Hengyang, 421001 China
语种:
英文
关键词:
immunogenic cell death;immunotherapy;nanoparticles
期刊:
Macromolecular Bioscience
ISSN:
1616-5187
年:
2023
卷:
23
期:
9
页码:
e2300093
基金类别:
National Key R&D Program of China [2018YFB1900201]; Hunan Science and Technology Innovation Leading Talent Project [2022RC3080]; Key R&D Program of Hunan province [2021SK2036]; Natural Science Foundation of Hunan province [2021JJ30603]; Research Foundation of Education Bureau of Hunan Province [21A0284]; Scientific Research Project of Hunan Provincial Health Commission [202113021875]
机构署名:
本校为第一机构
院系归属:
药学与生物科学学院
摘要:
This review summarizes four leading strategies used to promote the therapeutic effects of immunogenic cell death (ICD) via nanotechnology, including increasing the localized concentration of an ICD inducer in tumor, inducing various intracellular reactions, catalyzing the activity of antigen‐presenting cells, and protecting the function of cytotoxic T cells, together with an overview of the state‐of‐the‐art clinical applications of ICD via nanotechnology. Abstract Immunotherapy represents the most promising treatment strategy for cancer, bu...

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