期刊论文

Wang, Haohua(huazi8112@hainanu.edu.cn)

英文

Complexity

1076-2787

2022

2022

10.1155/2022/5181333

Hainan Province Science and Technology Special Fund [ZDYF2021SHFZ231]; National Natural Science Foundation of China [12261028, 11761025, 11961018]; Natural Science Foundation of Hainan Province [120RC451, 2019RC168]; Hainan Province Innovative Scientific Research Project for Graduate Students [Qhys2021-208]; Specific Research Fund of the Innovation Platform for Academicians of Hainan Province

本校为其他机构

The process of gene expression is affected by many extracellular stimulus signals, and the stochasticity of these signals reshapes gene expression. To adapt the fluctuation of the extracellular environment, genes have many strategies for augmenting their survival probability, frequency modulation, and amplitude modulation. However, it is unclear how genes utilize the stochasticity of signals to regulate gene expression and which strategy will be chosen to maximize cellular function. Here, we analyze a simple mechanistic model to clarify the eff...