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Diastereoselective Synthesis of CF3-Containing Vicinal Diamines

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成果类型:
期刊论文
作者:
Huang, Qiu-xia;Zheng, Qu-tong;Duan, Yaya;Lin, Jin-Hong;Xiao, Ji-Chang;Zheng, Xing
通讯作者:
Jin-Hong Lin<&wdkj&>Ji-Chang Xiao<&wdkj&>Xing Zheng
作者机构:
Institute of Pharmacy and Pharmacology, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, 28 Western Changsheng Road, Hengyang, Hunan 421001, China<&wdkj&>Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China
[Huang, Qiu-xia; Xiao, Ji-Chang; Zheng, Qu-tong; Zheng, Xing] Institute of Pharmacy and Pharmacology, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China , 28 Western Changsheng Road, Hengyang, Hunan 421001, China
[Huang, Qiu-xia; Duan, Yaya; Lin, Jin-Hong; Xiao, Ji-Chang; Zheng, Qu-tong; Zheng, Xing] Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences , 345 Lingling Road, Shanghai 200032, China
通讯机构:
[Xiao, JC; Zheng, X] Univ South China, Hunan Prov Cooperat Innovat Ctr Mol Target New Dr, Inst Pharm & Pharmacol, 28 Western Changsheng Rd, Hengyang 421001, Hunan, Peoples R China.
[Lin, JH; Xiao, JC; Zheng, X] Univ Chinese Acad Sci, Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, 345 Lingling Rd, Shanghai 200032, Peoples R China.
Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Road, Shanghai, China
语种:
英文
关键词:
Diastereoselective synthesis - Intermediate product - Two-step procedure
期刊:
Journal of Organic Chemistry
ISSN:
0022-3263
年:
2017
卷:
82
期:
15
页码:
8273-8281
基金类别:
National Basic Research Program of China [2015CB931900, 2012CBA01200]; National Natural Science Foundation [21421002, 21472222, 21502214, 21672242, 81273537]; Chinese Academy of Sciences [XDA02020105, XDA02020106]; Science and Technology Commission of Shanghai Municipality [15DZ1200102]; Key Research Program of Frontier Sciences (CAS) [QYZDJ-SSW-SLH049]; Key Project of Hunan Province Science and Technology Department [2016DK2001]; Key Project of Hunan Provincial Education Department [17A190]; Zhengxiang Scholar Program of the University of South China
机构署名:
本校为第一且通讯机构
院系归属:
药学与生物科学学院
摘要:
The highly diastereoselective synthesis of CF3-containing vicinal diamines by a convenient two-step procedure without the need to isolate the intermediate products is described.

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