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The protective functions of omentin in cardiovascular diseases

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成果类型:
期刊论文
作者:
Tan, Yu-Lin;Zheng, Xi-Long;Tang, Chao-Ke*
通讯作者:
Tang, Chao-Ke
作者机构:
[Tang, Chao-Ke; Tan, Yu-Lin] Univ South China, Key Lab Atherosclerol Hunan Prov, Life Sci Res Ctr, Inst Cardiovasc Res,Hunan Prov Cooperat Innovat C, Hengyang 421001, Hunan, Peoples R China.
[Tan, Yu-Lin] XiangNan Univ, Inst Pathol Res, Chenzhou 423000, Peoples R China.
[Zheng, Xi-Long] Univ Calgary, Hlth Sci Ctr, Dept Biochem & Mol Biol, Libin Cardiovasc Inst Alberta,Cumming Sch Med, Calgary, AB T2N 4N1, Canada.
[Tang, Chao-Ke] Univ South China, Key Lab Atherosclerol Hunan Prov, Life Sci Res Ctr, Hengyang 421001, Hunan, Peoples R China.
通讯机构:
[Tang, Chao-Ke] U
Univ South China, Key Lab Atherosclerol Hunan Prov, Life Sci Res Ctr, Hengyang 421001, Hunan, Peoples R China.
语种:
英文
关键词:
Cardiovascular diseases;Omentin;Protective functions
期刊:
Clinica Chimica Acta
ISSN:
0009-8981
年:
2015
卷:
448
页码:
98-106
基金类别:
The authors gratefully acknowledge the financial support from the National Natural Sciences Foundation of China ( 81170278 and 81370377 ), the Hunan Provincial Natural Science Fund of China ( 2015JJ2131 ), the Zhengxiang Scholar Program of University of South China ( 2014-004 ), the Graduate Student Science Research Innovation Project of University of South China ( 2015XCX03 ), and the Medical Research Plan Projects Foundation of Hunan Provincial Health Department ( B2014-070 ).
机构署名:
本校为第一且通讯机构
院系归属:
国防科学技术学院
医学院
药学与生物科学学院
摘要:
Adipose tissue is considered as a large gland that can produce paracrine and endocrine hormones. Growing evidence suggests that adipocytes may link obesity to cardiovascular diseases (CVD). Adipose tissue produces a large number of mediators, which affect metabolism, inflammation and coagulation. Omentin, a novel adipocytokine, has come into the center of interest due to its favorable effects on inflammation, glucose homeostasis and CVD. The present review provides a concise and general overview on the roles of omentin in CVD. The knowledge of these concepts ma...

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