Skull base chordoma and spinal chordoma exhibit consistency in terms of endoplasmic reticulum stress aspects

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成果类型：

期刊论文

作者：

Niu, Hua-Qing;Zheng, Bo-Yv;Zou, Ming-Xiang;Zhang, Tao-Lan;Zheng, Bo-Wen

通讯作者：

Zheng, BW

作者机构：

[Niu, Hua-Qing] Zhengzhou Univ, Affiliated Hosp 2, Dept Ophthalmol, Zhengzhou, Peoples R China.

[Zheng, Bo-Yv] Gen Hosp Cent Theater Command, Dept Orthoped Surg, Wuhan, Peoples R China.

[Zou, Ming-Xiang] Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Dept Spine Surg, Hengyang, Peoples R China.

[Zhang, Tao-Lan] Univ South China, Affiliated Hosp 1, Inst Clin Med, Hengyang Med Sch, Hengyang, Peoples R China.

[Zhang, Tao-Lan] Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Dept Pharm, Hengyang, Peoples R China.

通讯机构：

[Zheng, BW ] P

Peking Univ, Peking Univ Peoples Hosp, Musculoskeletal Tumor Ctr, 11 Xizhimen South St, Beijing 100044, Peoples R China.

语种：

英文

期刊：

NEURO-ONCOLOGY

ISSN：

1522-8517

年：

2024

卷：

期：

页码：

1171-1173

DOI：

10.1093/neuonc/noae050

基金类别：

National Natural Science Foundation of China [82003802, 82002364]; Natural Science Foundation of Hunan Province [2019JJ50542, 2023JJ50156, 2021JJ40509]; Hunan Provincial Natural Science Foundation for Excellent Youth Scholars [2023JJ20035]; Clinical Research 4310 Program of the First Affiliated Hospital of the University of South China [20224310NHYCG04]; Project for Clinical Research of Hunan Provincial Health Commission [20201978, 20201956]; Science and Technology Innovation Program of Hunan Province [2023RC3127]; China Scholarship Council [202106370071]

机构署名：

本校为其他机构

院系归属：

医学院

药学与生物科学学院

摘要：

We are honored by the comments made by Li et al.1 regarding our publication2 in Neuro-Oncology. Peer-to-peer communication fosters valuable exchanges that aid in promptly addressing issues, thereby enhancing the scientific rigor of research outcomes. In response to their inquiries, we have provided answers and conducted further investigations. Firstly, they indicate that RNA-Seq data were obtained from formalin-fixed paraffin-embedded (FFPE) samples of skull base chordoma and spinal chordoma, and RNA degradation in FFPE samples may influence the results. However, obtaining and preserving fresh...

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Skull base chordoma and spinal chordoma exhibit consistency in terms of endoplasmic reticulum stress aspects

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