[Zhang, Miao; Wei, Hua; Ma, Liwei; Liu, Fangjun] Lanzhou Univ, Key Lab Nonferrous Met Chem & Resources Utilizat, State Key Lab Appl Organ Chem, Lanzhou 730000, Gansu, Peoples R China.

[Zhang, Miao; Wei, Hua; Ma, Liwei; Liu, Fangjun] Lanzhou Univ, Coll Chem & Chem Engn, Lanzhou 730000, Gansu, Peoples R China.

[Wei, Hua; Wang, Dun; Yu, Cui-Yun] Univ South China, Hunan Prov Cooperat Innovat Ctr Mol Target New Dr, Hengyang 421001, Peoples R China.

[Wei, Hua; Wang, Dun; Yu, Cui-Yun] Univ South China, Dept Pharm & Pharmacol, Hengyang 421001, Peoples R China.

[Liwei Ma; Hua Wei] S

[Cui-Yun Yu] H

State Key Laboratory of Applied Organic Chemistry, Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, and College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, Gansu 730000, China<&wdkj&>Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study & Department of Pharmacy and Pharmacology, University of South China, Hengyang, 421001, China<&wdkj&>State Key Laboratory of Applied Organic Chemistry, Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, and College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, Gansu 730000, China<&wdkj&>Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study & Department of Pharmacy and Pharmacology, University of South China, Hengyang, 421001, China

Animals;Antineoplastic Agents;Doxorubicin;Drug Carriers;Drug Liberation;Micelles;Neoplasms;Polymers;Precision Medicine;Tumor Microenvironment;Biocompatibility;Chemotherapy;Controlled drug delivery;Diseases;Efficiency;Enzymes;Fluorescence;Hydrophilicity;Oncology;Targeted drug delivery;Tumors;alanine aminotransferase;aspartate aminotransferase;copolymer;creatinine;doxorubicin;fluorene derivative;lactate dehydrogenase;nitrogen;proteinase K;urea;antineoplastic agent;doxorubicin;drug carrier;polymer;Anti-cancer drug delivery;Cell imaging;Conjugated bottlebrush copolymer;Drug-loading efficiency;Enzyme-responsive;High drug loadings;Polyfluorenes;Theranostic micelle;Theranostics;Tumor microenvironments;alanine aminotransferase blood level;animal cell;animal experiment;animal model;animal tissue;Article;aspartate aminotransferase blood level;column chromatography;controlled study;creatinine blood level;degree of polymerization;dispersity;drug degradation;drug delivery system;drug release;encapsulation;female;fluorescence;fluorescence resonance energy transfer;IC50;in vitro study;in vivo study;molecular weight;mouse;nonhuman;polymerization;proton nuclear magnetic resonance;quantum yield;Suzuki reaction;synthesis;theranostic nanomedicine;transmission electron microscopy;tumor volume;tumor weight;urea nitrogen blood level;uterine cervix carcinoma;animal;chemistry;micelle;neoplasm;personalized medicine;tumor microenvironment;Micelles

药学与生物科学学院