The authors appreciate Ying Yang, Yongqiang Zhou, Hao Chen, Xiaoou Wang, for their help with collecting samples and lipid measurements; Li Tian and Mingde Fu for scientific discussions and mentorship. This work was supported by the Research Foundation of Education Bureau of Hunan Province, China (No. 15B211), and the Cooperative Innovation Center for Molecular Target New Drug Study, Hunan Province, China.