Preparation of urchin-like Pd-Pt-Ir nanozymes and their application for the detection of ascorbic acid and hydrogen peroxide

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成果类型：

期刊论文

作者：

He, Jian;He, Dongxiu;Yang, Lin;Wu, Gui-Long;Tian, Jinming;...

通讯作者：

Wang, WG

作者机构：

[Liu, Ying; Wang, Weiguo; Yang, Lin; He, Jian; He, Dongxiu; Tian, Jinming] Univ South China, Inst Pharm & Pharmacol, Hengyang 421000, Hunan, Peoples R China.

[Liu, Ying; Wang, Weiguo; Yang, Lin; He, Jian; He, Dongxiu; Tian, Jinming] Hunan Prov Cooperat Innovat Ctr Mol Target New Dr, Hengyang, Hunan, Peoples R China.

[Liu, Ying; Wang, Weiguo; Yang, Lin; He, Jian; He, Dongxiu; Tian, Jinming] Hunan Xinhexin Biol Med Co Ltd, Pharm Grad Educ Innovat Base, Hengyang, Hunan, Peoples R China.

[Wu, Gui-Long] Univ South China, Med Instrument & Equipment Technol Lab, Hengyang Med Coll, Hengyang 421000, Hunan, Peoples R China.

通讯机构：

[Wang, WG ] U

Univ South China, Inst Pharm & Pharmacol, Hengyang 421000, Hunan, Peoples R China.

Hunan Prov Cooperat Innovat Ctr Mol Target New Dr, Hengyang, Hunan, Peoples R China.

Hunan Xinhexin Biol Med Co Ltd, Pharm Grad Educ Innovat Base, Hengyang, Hunan, Peoples R China.

语种：

英文

关键词：

Ascorbic acid;Nanozyme;Trimetallic;Colorimetric detection;Nanoparticles;Nanocomposites

期刊：

Materials Letters

ISSN：

0167-577X

年：

2022

卷：

314

页码：

131851

DOI：

10.1016/j.matlet.2022.131851

基金类别：

In this work, an urchin-like trimetal Pd-Pt-Ir nanozyme was prepared by the seeding method and characterized by TEM, SEM and XPS. The results demonstrate that Pd-Pt-Ir nanozyme possesses better peroxidase-like activity compared to Pd-Pt nanozyme due to the doping of Ir. Based on the peroxidase-like activity, a rapid colorimetric detection platform was constructed by using the Pd-Pt-Ir nanozyme as a simulated enzyme. Moreover, the application of this nanozyme in AA and H2O2 detection was

机构署名：

本校为第一且通讯机构

院系归属：

药学与生物科学学院

摘要：

The urchin-like trimetallic nanozyme Pd-Pt-Ir was firstly prepared through atomic replication. Due to the high affinity to H2O2, the activity of Pd-Pt-Ir is higher than that of Pd-Pt. Based on this concept, Pd-Pt-Ir was applied for the detection of ascorbic acid and hydrogen peroxide. The linear range of ascorbic acid and hydrogen peroxide were 25-800 mu M and 3.9-62.5 mM, respectively, and the LODs were11.7 mu M and 3.6 mM, respectively. Furthermore, the Pd-Pt-Ir nanozyme was applied for the rapid detection of ascorbic acid, and a test strip was built. Ascorbic acid concentrations ranging fro...

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Preparation of urchin-like Pd-Pt-Ir nanozymes and their application for the detection of ascorbic acid and hydrogen peroxide

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