The maximal clique problem is an NP (nondeterministic polynomial time)-complete problem. We present an algorithm that solves maximal clique problem within the framework of a surface-based model of computation. The time complexity of our algorithm is O(n2), and the number of kinds of short oligonucleotides needed to encode maximal clique problem is n + 3, where n is the size of the graph. In our algorithm, immobilizing DNA (deoxyribonucleic acid) strands to a solid surface reduces the possibility of error resulting from the loss of DNA strands in solution. A solution-based algorithm solving max...
