期刊论文

Chao-Ke, T.

中文

中国药理学通报

1001-1978

2000

16

5

563-567

10.3321/j.issn:1001-1978.2000.05.026

本校为第一机构

目的　探讨绞股蓝总皂苷 （GPS）对注射内毒素的家兔血流动力学和继发DIC的影响。方法　动物静脉麻醉后 ,取血测量血液某些指标和NO水平。通过二道生理记录仪和SMUP A型生物信号处理仪测量血压及血流动力学指标。动物处死后 ,取血再次测量血液某些指标和NO水平。结果　对照组实验前后各指标没有出现明显的变化 （P >0 0 5 ）。内毒素 （LPS）组血流动力学指标在实验后 4h、6h时与实验前和对照组比较P

AIM: To investigate the effects of gypenosides(GPS) on hemodynamics and nitric oxide levels in rabbits with endotoxin induced disseminated intravascular coagulation. METHODS: Rabbits were randomly divided into three groups, control, endotoxin (LPS), and endotoxin plus gypenosides. The animals were anaethetized with intravenous injection of 20% ethyl urethane. Nitric oxide levels were determined by the method of colorimetric analysis. The parameters of hemodynamics were measured by SMUP-A, a bioinfomatic processor. The count of platelet, plasma ...