Objective To explore the relationship between hyperuricemia and cardiovascular diseases (CVD). Methods Papers of prospective studies concerning the relationship between hyperuricemia and CVD published in English from 1996 to 2006 were collected by computer searching in Medline and Highwire Press data base. Dersimonian - laird method of random effect model was applied to deal with the data. Results 10 prospective studies meeting the criterion were included in this article. The total samples were 35 930, 3345 cases of them were patients. The RR...