Crosstalk between autophagy and epithelial-mesenchymal transition and its application in cancer therapy

首页 > 成果 > 详情

认领

导出

下载 Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Chen, Hong-Tao;Liu, Hao;Mao, Min-Jie;Tan, Yuan;Mo, Xiang-Qiong;...

通讯作者：

Jiang, Guan-Min;Shan, Hong

作者机构：

[Liu, Yan; Tan, Yuan; Jiang, Guan-Min; Chen, Hong-Tao] Sun Yat Sen Univ, Affiliated Hosp 5, Dept Clin Lab, Zhuhai 2528000, Guangdong, Peoples R China.

[Liu, Hao] Guangzhou Med Univ, Canc Hosp, Guangzhou, Guangdong, Peoples R China.

[Liu, Hao] Guangzhou Med Univ, Canc Res Inst, Guangzhou, Guangdong, Peoples R China.

[Mao, Min-Jie] Sun Yat Sen Univ, Collaborat Innovat Ctr Canc Med, Dept Lab Med, State Key Lab Oncol South China,Canc Ctr, Guangzhou, Guangdong, Peoples R China.

[Tan, Yuan] Cent S Univ, Dept Clin Lab, Hunan Canc Hosp, Affiliated Canc Hosp,Xiangya Sch Med, Changsha, Hunan, Peoples R China.

通讯机构：

[Jiang, Guan-Min; Shan, Hong] S

Sun Yat Sen Univ, Affiliated Hosp 5, Dept Clin Lab, Zhuhai 2528000, Guangdong, Peoples R China.

Sun Yat Sen Univ, Guangdong Prov Key Lab Biomed Imaging, Affiliated Hosp 5, Zhuhai 2528000, Guangdong, Peoples R China.

语种：

英文

关键词：

Autophagy;Epithelial-mesenchymal transition;Cancer metastasis;Anticancer therapy

期刊：

Molecular Cancer

ISSN：

1476-4598

年：

2019

卷：

期：

页码：

1-19

DOI：

10.1186/s12943-019-1030-2

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81502104, 81430041, 81620108017]; National Program on Key Basic Research ProjectNational Basic Research Program of China [2018YFC0910600]; Hunan Young Talent [2017RS3051]; Key Laboratory of Biomedical Imaging of Guangdong Province [2018B030322006]

机构署名：

本校为其他机构

院系归属：

医学院

摘要：

Autophagy is a highly conserved catabolic process that mediates degradation of pernicious or dysfunctional cellular components, such as invasive pathogens, senescent proteins, and organelles. It can promote or suppress tumor development, so it is a “double-edged sword” in tumors that depends on the cell and tissue types and the stages of tumor. The epithelial-mesenchymal transition (EMT) is a complex biological trans-differentiation process that allows epithelial cells to transiently obtain mesenchymal features, including motility and metasta...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Crosstalk between autophagy and epithelial-mesenchymal transition and its application in cancer therapy

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问