期刊论文

Zhang, C

英文

European Journal of Pharmacology

0014-2999

2024

979

176857

10.1016/j.ejphar.2024.176857

Sources of funding This work was supported by the Projects Supported by Scientific Research Fund of Hunan Provincial Education Department (21A0283, 23A0315). CRediT authorship contribution statement Yuan Tian: Writing – original draft, Visualization, Software, Resources, Conceptualization. Yi-Fan Liu: Writing – original draft, Visualization, Software, Resources, Conceptualization. Yan-Yue Wang: Writing – original draft, Visualization, Software, Resources, Conceptualization. Yong-Zhen Li: Writing – original draft, Software. Wen-Yan Ding: Writing – original draft, Software. Chi Zhang: Writing – review & editing, Supervision, Resources, acquisition, Conceptualization.

本校为第一且通讯机构

Atherosclerosis is a chronic inflammatory disease of the arterial wall caused by an imbalance of lipid metabolism and a maladaptive inflammatory response. A variety of harmful cellular changes associated with atherosclerosis include endothelial dysfunction, the migration of circulating inflammatory cells to the arterial wall, the production of proinflammatory cytokines, lipid buildup in the intima, local inflammatory responses in blood vessels, atherosclerosis-associated apoptosis, and autophagy. PTEN inhibits the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB/AKT)/mammalian target...