期刊论文

Effect of exosomes as drug carriers in chemotherapy of pancreatic cancer

中文

中南大学学报(医学版)

1672-7347

2023

48

02

268-274

10.11817/j.issn.1672-7347.2023.220439

2020JJ4053:湖南省自然科学基金项目 KQ2004130:长沙市科技项目

本校为第一机构

胰腺癌(pancreatic cancer,PC)是预后极差的消化道恶性肿瘤。PC的发病率仍在持续增长,其5年生存率仅为10%。手术切除是当前治疗PC最有效的手段,但有80%的患者诊断为PC时已错过手术最佳时间。化学治疗...展开更多 胰腺癌(pancreatic cancer,PC)是预后极差的消化道恶性肿瘤。PC的发病率仍在持续增长,其5年生存率仅为10%。手术切除是当前治疗PC最有效的手段,但有80%的患者诊断为PC时已错过手术最佳时间。化学治疗(简称化疗)是PC的主要治疗方式之一,但PC对化疗不敏感、容易产生耐药且不良反应多,这与化疗药物缺乏靶向性有关。外泌体是一种几乎所有类型细胞都可分泌的纳米级囊泡,携带有各种生物活性物...

Pancreatic cancer (PC) is a malignant tumor of the digestive tract with poor patientprognosis. The PC incidence is still increasing with a 5-year survival rate of only 10%. Atpresent, surgical resection is the most effective method to treat PC, however, 80% of thepatien...MORE Pancreatic cancer (PC) is a malignant tumor of the digestive tract with poor patientprognosis. The PC incidence is still increasing with a 5-year survival rate of only 10%. Atpresent, surgical resection is the most effective method to treat PC, however, 80% of thepatients missed the best time for surgery after they have ...