期刊论文

Long, Dingxin

英文

Acta Histochemica

0065-1281

2023

125

2

152000

10.1016/j.acthis.2023.152000

This work was supported by the National Natural Science Foundation of China (81673227), the Natural Science Foundation of Hunan Province (2020JJ4080), and the Hunan Provincial Innovation Foundation for Postgraduates (CX20210963 and CX20221026). CRediT authorship contribution statement The first draft of the manuscript was written, reviewed and edited by Zehui Hu. Shengyuan Shi: contributed to the Conceptualization of manuscript. Fangyan Hu: contributed to the Conceptualization of manuscript. Yiquan Ou: contributed to the Conceptualization of manuscript. Dingxin Long provided the Supervision and acquisition. All authors approved the final manuscript.

本校为第一机构

Mitochondria-associated endoplasmic reticulum membranes (MAMs) are dynamic suborganelle membranes that physically couple endoplasmic reticulum (ER) and mitochondria to provide a platform for exchange of intracellular molecules and crosstalk between the two organelles. Dysfunctions of mitochondria and ER and imbalance of intracellular homeostasis have been discovered in the research of toxics. Cellular activities such as oxidative stress, ER stress, Ca2+ transport, autophagy, mitochondrial fusion and fission, and apoptosis mediated by MAMs are closely related to the toxicological effects of var...