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Mitochondrial dysfunction in polycystic ovary syndrome

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成果类型:
期刊论文
作者:
Zeng, Xin;Huang, Qin;Long, Shuang Lian;Zhong, Qiaoqing*;Mo, Zhongcheng*
通讯作者:
Zhong, Qiaoqing;Mo, Zhongcheng
作者机构:
[Zeng, Xin; Long, Shuang Lian; Huang, Qin; Mo, Zhongcheng] Univ South China, Hengyang Med Sch, Clin Anat & Reprod Med Applicat Inst, Dept Histol & Embryol, Hengyang, Hunan, Peoples R China.
[Zhong, Qiaoqing] Cent South Univ, Xiangya Hosp, Dept Cardiovasc Med, Changsha 410008, Peoples R China.
[Mo, Zhongcheng] Guilin Med Univ, Inst Basic Med Sci, Guilin 541100, Guangxi, Peoples R China.
通讯机构:
[Zhong, Qiaoqing] C
[Mo, Zhongcheng] G
Cent South Univ, Xiangya Hosp, Dept Cardiovasc Med, Changsha 410008, Peoples R China.
Guilin Med Univ, Inst Basic Med Sci, Guilin 541100, Guangxi, Peoples R China.
语种:
英文
关键词:
follicular development;mitochondrion;polycystic ovary syndrome;reproductive metabolism
期刊:
DNA AND CELL BIOLOGY
ISSN:
1044-5498
年:
2020
卷:
39
期:
8
页码:
1401-1409
基金类别:
Natural Sciences Foundation of Hunan ProvinceNatural Science Foundation of Hunan Province [2019JJ40248, 2018JJ2663]; Key Lab for Clinical Anatomy & Reproductive Medicine of Hengyang City [2017KJ182]; Chuanshan Talents Project in the University of South China
机构署名:
本校为第一机构
院系归属:
医学院
摘要:
Polycystic ovary syndrome (PCOS) is one of the most common female reproductive metabolisms. It is an endocrine disease that affects reproductive women and often exhibits with hyperandrogenemia, insulin resistance (IR), low inflammation, and an increased risk of type 2 diabetes mellitus, metabolic syndrome, and cardiovascular events such as hypertension and dyslipidemia in patients. However, the molecular mechanism of PCOS is still unclear. Recently, an increasing number of studies have shown that the oxidative stress induced by mitochondrial dysfunction has negative effects on IR, lipid metabo...

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