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Detection of radon with biosensors based on the lead(II)-induced conformational change of aptamer HTG and malachite green fluorescence probe

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成果类型:
期刊论文
作者:
Li, Shiya;Liu, Hongwen;Yang, Guiying;Liu, Shimeng;Liu, Ran;...
通讯作者:
Lv, Changyin
作者机构:
[Liu, Shimeng; Li, Shiya; Yang, Guiying; Lv, Changyin; Liu, Hongwen; Liu, Ran] Univ South China, Coll Publ Hlth, Hengyang 421001, Peoples R China.
通讯机构:
[Lv, Changyin] U
Univ South China, Coll Publ Hlth, Hengyang 421001, Peoples R China.
语种:
英文
关键词:
Environmental monitoring;Fluorescence detection;Lead;Radiation damage;Radon
期刊:
Journal of Environmental Radioactivity
ISSN:
0265-931X
年:
2018
卷:
195
页码:
60-66
基金类别:
Acknowledgments Funding: This work was supported by the National Natural Science Foundation of China [grant numbers 81473021].
机构署名:
本校为第一且通讯机构
院系归属:
公共卫生学院
摘要:
The aim of this paper is to assemble a new biosensor for detecting the accumulated radon dose in the environment to achieve rapid monitor of radon. Based on the correlation between radon and its stable decay daughter Pb-210, a biosensor using the lead-induced specific aptamer HTG conformational changes, and the organic dye malachite green (MG) as a fluorescent probe was assembled. In these studies, we explored a novel, sensitive, label-free, fluorescence biosensing method for the detection of both radon and lead. The fluorescence intensity difference has a linear relationship with Pb2+ and the...

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