Amplified electrochemical determination of UO2 2+ based on the cleavage of the DNAzyme and DNA-modified gold nanoparticle network structure

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Cao, Chen;Liu, Jinquan;Tang, Shuangyang;Dai, Zhongran;Xiao, Fubing;...

通讯作者：

Yuan, Yali;Li, Le

作者机构：

[Yuan, Yali; Cao, Chen] Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Hunan, Peoples R China.

[Liu, Ling; Liu, Jinquan; Rang, Weiqing; Chen, Tuo; Li, Le; Xiao, Fubing] Univ South China, Sch Publ Hlth, Hengyang 421001, Hunan, Peoples R China.

[Liu, Jinquan; Li, Le; Xiao, Fubing] Univ South China, Key Lab Hlth Hazard Factors Inspect & Quarantine, Hengyang 421001, Peoples R China.

[Liu, Jinquan] Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China.

[Tang, Shuangyang] Univ South China, Inst Pathogen Biol, Hengyang 421001, Peoples R China.

通讯机构：

[Yuan, Yali; Li, Le] U

Univ South China, Sch Chem & Chem Engn, Hengyang 421001, Hunan, Peoples R China.

Univ South China, Sch Publ Hlth, Hengyang 421001, Hunan, Peoples R China.

Univ South China, Key Lab Hlth Hazard Factors Inspect & Quarantine, Hengyang 421001, Peoples R China.

Univ South China, Hunan Prov Key Lab Green Dev Technol Extremely Lo, Hengyang 421001, Peoples R China.

语种：

英文

关键词：

deoxyribozyme;drinking water;gold;immobilized nucleic acid;metal nanoparticle;methylene blue;uranium derivative;uranium dioxide;chemistry;electrochemical analysis;genetic procedures;limit of detection;procedures;reproducibility;river;water pollutant;Biosensing Techniques;DNA, Catalytic;Drinking Water;Electrochemical Techniques;Gold;Immobilized Nucleic Acids;Limit of Detection;Metal Nanoparticles;Methylene Blue;Reproducibility of Results;Rivers;Uranium Compounds;Water Pollutants, Chemical

期刊：

Microchimica Acta

ISSN：

0026-3672

年：

2020

卷：

187

期：

页码：

311

DOI：

10.1007/s00604-020-04263-1

基金类别：

This research was supported by the Key R&D Program of Hunan Province (2018SK2029), the National Natural Science Foundation of China (11405081, 21906077), the Natural Science Foundation of Hunan Province (2018JJ3452), the Open Project Program of the State Key Laboratory of Chemo/Biosensing and Chemometrics, Hunan University (2018010), the science and technology project of Hengyang (2018KJ123), and the Fund of Hengyang Key Laboratory (2018KJ110).

机构署名：

本校为第一且通讯机构

院系归属：

化学化工学院

医学院

公共卫生学院

摘要：

A superior electrochemical biosensor was designed for the determination of UO2 2+ in aqueous solution by integration of DNAzyme and DNA-modified gold nanoparticle (DNA-AuNP) network structure. Key features of this method include UO2 2+ inducing the cleavage of the DNAzyme and signal amplification of DNA-AuNP network structure. In this electrochemical method, the DNA-AuNP network structure can be effectively modified on the surface of gold electrode and then employed as an ideal signal amplification unit to generate amplified electrochemical res...

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Amplified electrochemical determination of UO2 2+ based on the cleavage of the DNAzyme and DNA-modified gold nanoparticle network structure

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