In order to improve the solubility and the long-cycle performance of hydrophobic drug sorafenib (SOR), and to obtain an ideal smart drug delivery system for the effective treatment of liver cancer, S-SMIP, a pH/GSH double-sensitive sorafenib stealth imprinting material, was successfully prepared by UV-initiated surface imprinted polymerization on the basis of polyethylene glycol 2000 (PEG(2000)) acted as "gate keeper " modified magnetic substrate. The results showed that S-SMIP had a good adsorption capacity of 260.0 mg g(-1) and an excellent selectivity factor alpha 2.33. S-SMIP's kinetic ads...
