NSFCNational Natural Science Foundation of China (NSFC) [21372063]; Program for Changjiang Scholars and Innovative Research Team in UniversityProgram for Changjiang Scholars & Innovative Research Team in University (PCSIRT) [PCS IRT1126]
机构署名：
本校为其他机构
院系归属：
药学与生物科学学院
摘要：
A near-infrared (NIR) "off-on" fluorescent probe BDP-680 was developed by taking advantage of the Michael addition reaction of unsaturated double bonds in conformationally restricted BODIPY to allow detection of H2S. The new probe possesses a highly selective and sensitive response to H2S. Such a NIR probe has been applied successfully to detect H2S in 10% deproteinized fetal bovine serum (FBS). The detection limit of the probe for NaSH in 10% deproteinized FBS sample was calculated to be about 1 μM which is consistent with the value obtained from serum free solutions (0.5 μM). The probe...
