期刊论文

中文

Zhongguo Xinsheng Erke Zazhi

1673-6710

2011

26

2

99-101

10.3969/j.issn.1673-6710.2011.02.07

本校为第一机构

目的 探讨铁代谢紊乱在新生儿缺氧缺血性脑病(HIE)再灌注损伤中的作用.方法 分别测定60例HIE足月新生儿(其中轻度30例,中度20例,重度10例)入院时(日龄48 h内)、日龄3～5天时血清铁(SI)及血清铁蛋白(SF)含量,并与20名健康新生儿(对照组)进行比较.结果 轻、中、重度HIE组入院时SI分别为(9.8±3.6)μmol/L、(9.7±4.3)μmol/L和(7.8±2.7)μmol/L,均低于对照组(14.5±5.0)μmol/L(P均＜0.05);入院时轻、中、重度HIE组SF分别为(145.2±59.9)μg/L、(141.7±30.8)μg/L和(110.6±29.0)μg/L,均低于对照组(216.0±90.0)μg/L(P均＜0.05);轻、中、重度HIE组日龄3～5天时SI分别为(18.7±4.2)μmol/L、(1...

Objective To study the effect of iron metabolic disorder in neonatal hypoxic-ischemic encephalopathy（HIE）.Methods To measure the serum iron and serum ferritin levels in 60 neonates of HIE within 48 h after birth and day 3-5 after birth,which including 30 neonates in mild HIE,20 in moderate HIE and 10 in severe HIE.And 20 healthy neonates＇ serum iron and serum ferritin level had been measured within 48 h after birth and day 3-5 after birth as control group.Results The level of serum iron in mild,moderate,severe HIE within 48 h after birth wer...