期刊论文

Tan, Tan;Luo, Dixian

英文

Cell and Bioscience

2045-3701

2016

6

1

1-10

10.1186/s13578-016-0082-x

This work was supported by the grants from the National Natural Science Foundation of China (Grant number 81372825, 81300429); the China Postdoctoral Science Foundation (No. 2015M582340); the Strategic New Industrialization Special Project of Hunan Province (XCQZ2015-68);the Education Department Project of Hunan Province (13C882); the Health Department project of the Hunan Province (B2012-157); and the Young Natural Science Foundation of Chenzhou (CZ2013063); the Foreign Intelligence Introduction Project (CCSZ2015-116). We are very grateful for Mr. Zhuo Li (Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences) to provide us the lentivirus vector pSIN-EF2-Puromycin. We deeply appreciate Prof. Zhiqiang Xiao (Central South University, China) for providing CNE-2 cell line, and also indebted to all members of Translational Medicine Institute, Affiliated the First People’s Hospital of Chenzhou, University of South China for their kind help in experiments.

本校为第一且通讯机构

Background: Nasopharyngeal carcinoma (NPC) is one of the most common human head and neck cancers with high incidence in Southern China, Southeast Asia and North Africa. Because of its nonspecific symptoms, the early diagnosis of NPC is very difficult. The 5-year survival rate is not ideal in spite of great innovations in radiation and chemotherapy treatments. Highly sensitive and specific prognostic biomarkers are eager for NPC clinical diagnosis. To find specific target molecules is very important for individualized treatment. Aldo-keto reduct...