Anti-granulocyte autoantibody (AGAB) IgG was repeatedly assayed by chemoluminescent immunoassay and immuno-fluorescence test in 24 patients of kidney transplantation. In 2 of the patients,blood AGAB IgG was positive before operation but turned negative 2 weeks after transplantation. Blood AGAB IgG became positive after trnaplantation in 5 and neutropenia was noted in 3 of them, repeated acute rejections in 4.In 2 patients, both neutropenia and repeated acute rejections occurred. It was suggested that autoimmunity might also play a role in post-transplantation neutropenia and acute rejection of...
