Advances in the design and application of glycolysis-related nanodelivery systems for anti-tumor

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Zhou, Yanghui;Liu, Meijing;Lu, Na;Deng, Xiangping;Chen, Xin;...

通讯作者：

Tang, Guotao;Wang, Z

作者机构：

[Wang, Zhe; Tang, Lijing; Yang, Xiaoyan; Tang, Guotao; Wang, Z; Liu, Meijing; Xie, Zhizhong; Tang, GT; Zhou, Yanghui] Univ South China, Affiliated Hosp 2, Inst Pharm & Pharmacol,Dept Pharm, Hunan Prov Key Clin Lab Basic & Clin Pharmacol Res, Hengyang 421001, Hunan, Peoples R China.

[Wang, Zhe; Tang, Lijing; Yang, Xiaoyan; Tang, Guotao; Liu, Meijing; Xie, Zhizhong; Lei, Xiaoyong; Zhou, Yanghui] Univ South China, Hengyang Med Sch, Hengyang 421001, Hunan, Peoples R China.

[Lu, Na] Univ South China, Sch Nursing, Hengyang Med Sch, Hengyang 421001, Hunan, Peoples R China.

[Deng, Xiangping] Univ South China, Affiliated Hosp 1, Dept Pharm, Hengyang 421001, Hunan, Peoples R China.

[Chen, Xin] North Sichuan Med Coll, Innovat Ctr Sci & Technol, Nanchong 637000, Sichuan, Peoples R China.

通讯机构：

[Tang, GT; Wang, Z ] U

Univ South China, Affiliated Hosp 2, Inst Pharm & Pharmacol,Dept Pharm, Hunan Prov Key Clin Lab Basic & Clin Pharmacol Res, Hengyang 421001, Hunan, Peoples R China.

语种：

英文

关键词：

Anti-tumor nanodelivery systems;Drug delivery systems;Glycolysis pathway

期刊：

Colloids and Surfaces B: Biointerfaces

ISSN：

0927-7765

年：

2025

卷：

254

页码：

114844

DOI：

10.1016/j.colsurfb.2025.114844

基金类别：

National Natural Science Foundation of China [82304420, 82104172, 82404434]; Natural Science Foundation of Hunan Province [2023JJ40576, 2023JJ40575, 2024JJ6405]; Foundation of Hunan Provincial Key Laboratory [2019TP1041, 2023TP1014]; Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study

机构署名：

本校为第一且通讯机构

院系归属：

药学与生物科学学院

护理学院

摘要：

Hypoxia is a common feature of solid tumors, and activation of hypoxia-inducing factors in the tumor hypoxia microenvironment can lead to complex reprogramming of glucose metabolism in tumor cells. In particular, the unique glucose metabolism pattern of tumor cells, mainly glycolysis pathway, provides conditions for tumor growth, metastasis, immune escape and drug resistance. Drug development for glycolysis-related targets is more targeted and safer than traditional chemotherapy drugs, and drug delivery systems offer favorable strategies for improving the targeted therapy of these drugs in viv...

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Advances in the design and application of glycolysis-related nanodelivery systems for anti-tumor

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