sources This study was supported by the National Natural Science Foundation of China (81573193), the Natural Science Foundation of Hunan Province (2020JJ4082).
机构署名：
本校为第一机构
院系归属：
医学院
公共卫生学院
摘要：
Beryllium and its compounds can cause pulmonary interstitial fibrosis through mechanisms that are not yet clear. Long non-coding RNA (lncRNA) is implicated in various diseases. The molecular toxicity of beryllium sulfate (BeSO(4)) was investigated through the RNA-seq analysis of the lncRNA and mRNA whole-transcriptome of BeSO(4)-treated 16HBE cells. A total of 1014 lncRNAs (535 upregulated and 479 downregulated) and 4035 mRNAs (2224 upregulated and 1811 downregulated) were found to be significantly dysregulated (|logFC|≥>2.0, p
