Endometrial microbiome during early pregnancy among women with and without chronic endometritis: a pilot study

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成果类型：

期刊论文

作者：

Gao, Hong;Lu, Na;Chen, Yahui;Li, Genlin;Li, Huanhuan;...

通讯作者：

Wen, SW;Wang, XL;Connor, K

作者机构：

[Gao, Hong] Univ South China, Affiliated Hosp 2, Hengyang Med Sch, Sci Res Dept, Hengyang, Hunan, Peoples R China.

[Corsi, Daniel J.; Gao, Hong; Chen, Innie; Gale, Jenna; Wen, Shi Wu] Ottawa Hosp, Ottawa Hosp Res Inst, Ottawa, ON, Canada.

[Chen, Yahui; Lu, Na] Univ South China, Sch Nursing, Hengyang, Hunan, Peoples R China.

[Li, Genlin; Wang, Xiaolan] Univ South China, Hengyang Med Sch, Affiliated Hosp 1, Ctr Combinat Obstet & Gynecol & Reprod Med, Hengyang, Hunan, Peoples R China.

[Li, Huanhuan] Univ South China, Hengyang Med Sch, Affiliated Hosp 2, Dept Gynecol, Hengyang, Hunan, Peoples R China.

通讯机构：

[Connor, K ] C

[Wen, SW ] O

[Wang, XL ] U

Ottawa Hosp, Ottawa Hosp Res Inst, Ottawa, ON, Canada.

Univ South China, Hengyang Med Sch, Affiliated Hosp 1, Ctr Combinat Obstet & Gynecol & Reprod Med, Hengyang, Hunan, Peoples R China.

语种：

英文

关键词：

16S rRNA;chronic endometritis;early pregnancy;endometrial microbiome;host factors

期刊：

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY

ISSN：

2235-2988

年：

2025

卷：

页码：

1615182

DOI：

10.3389/fcimb.2025.1615182

基金类别：

China Scholarship Council10.13039/501100004543

机构署名：

本校为第一且通讯机构

院系归属：

护理学院

摘要：

INTRODUCTION: Although chronic endometritis (CE) is strongly associated with infertility and adverse pregnancy outcomes, the specific microbiome of women with CE who can conceive remain unclear. METHODS: This study recruited 100 participants aged 18 to 45 years with spontaneously conceived pregnancy who opted for pregnancy termination, detected their endometrial microbiome by 16S rRNA, and made a diagnosis of CE. RESULTS: Among them, 19 were diagnosed with CE. There was a comparable microbial composition within the endometrium between women with and without CE. The relative abundance of Sphing...

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Endometrial microbiome during early pregnancy among women with and without chronic endometritis: a pilot study

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