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Cyclodextrin-functionalized polymers as drug carriers for cancer therapy

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成果类型:
期刊论文
作者:
Wei, Hua;Yu, Cui-yun
通讯作者:
Wei, H.
作者机构:
[Wei, Hua] Key Laboratory of Nonferrous Metals Chemistry and Resources Utilization of Gansu Province, and Department of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, Gansu 730000, China. weih@lzu.edu.cn
通讯机构:
[Wei, Hua] Lanzhou Univ, Key Lab Nonferrous Met Chem & Resources Utilizat, Lanzhou 730000, Gansu, Peoples R China.
Key Laboratory of Nonferrous Metals Chemistry and Resources Utilization of Gansu Province, Department of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, Gansu, China
语种:
英文
关键词:
Cyclic molecules - Different structure - Functionalizations - Functionalized polymers - Hostguest chemistry - Polymer Chemistry - Research fields - State of the art
期刊:
Biomaterials Science
ISSN:
2047-4830
年:
2015
卷:
3
期:
7
页码:
1050-1060
基金类别:
National Natural Science Foundation of China [51473072, 81471777, 81102409]; Fundamental Research Funds for the Central Universities [lzujbky-2014-68]
机构署名:
本校为其他机构
院系归属:
药学与生物科学学院
摘要:
Cyclodextrins (CDs) represent the most extensively investigated cyclic molecules due to their wide availability, facile functionalization, unique amphiphilicity and inclusion capacity. The marriage of CD chemistry with polymer science has generated novel biomaterials by integrating supermolecular host-guest chemistry and state-of-the-art polymer chemistry techniques. The current mini-review focuses on the recent progress in CD-functionalized polymers as drug carriers for cancer therapy. CD-functionalized polymers with different structures are summarized. Their application as drug carriers for cancer therapy is then highlighted. In the end, the future directions of this rapidly developing research field are discussed. This journal is ©The Royal Society of Chemistry.

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