Host Response to Biomaterials for Cartilage Tissue Engineering: Key to Remodeling

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Wei, Fu;Liu, Shuyun;Chen, Mingxue;Tian, Guangzhao;Zha, Kangkang;...

通讯作者：

Guo, Quanyi(doctorguo_301@163.com);Chen, Zhiwei(czw9915@sina.com)

作者机构：

[Yang, Zhen; Zha, Kangkang; Sui, Xiang; Liu, Shuyun; Tian, Guangzhao; Guo, Quanyi; Wei, Fu] Chinese Peoples Liberat Army Gen Hosp, Inst Orthped, Beijing Key Lab Regenerat Med Orthoped, Key Lab Musculoskeletal Trauma & War Injuries PLA, Beijing, Peoples R China.

[Chen, Zhiwei; Li, Muzhe; Wei, Fu] Univ South China, Dept Orthped, Affiliated Hosp 1, Hengyang, Peoples R China.

[Chen, Mingxue] Peking Univ, Beijing Jishuitan Hosp, Dept Orthped Surg, Clin Coll 4, Beijing, Peoples R China.

[Yang, Zhen; Zha, Kangkang; Tian, Guangzhao] Nankai Univ, Sch Med, Tianjin, Peoples R China.

[Jiang, Shuangpeng] China Med Univ, Hosp 1, Shenyang, Peoples R China.

通讯机构：

[Guo, Q.] B

[Chen, Z.] D

Beijing Key Lab of Regenerative Medicine in Orthopedics, China

Department of Orthopedics, China

语种：

英文

关键词：

Biomaterials;Immunomodulation;macrophage;Tissue Engineering;Cartilage

期刊：

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY

ISSN：

2296-4185

年：

2021

卷：

页码：

664592

DOI：

10.3389/fbioe.2021.664592

基金类别：

This work was supported by the National Key R&D Program of China (2018YFC1105900) and the Chinese PLA General Hospital Medical Youth Program (QNC19042).

机构署名：

本校为其他机构

摘要：

Biomaterials play a core role in cartilage repair and regeneration. The success or failure of an implanted biomaterial is largely dependent on host response following implantation. Host response has been considered to be influenced by numerous factors, such as immune components of materials, cytokines and inflammatory agents induced by implants. Both synthetic and native materials involve immune components, which are also termed as immunogenicity. Generally, the innate and adaptive immune system will be activated and various cytokines and infla...

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Host Response to Biomaterials for Cartilage Tissue Engineering: Key to Remodeling

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