Musclin is a skeletal muscle-derived secreted peptide,which is involved in the homeostasis of glucose and lipid metabolism.The musclin play a role in skeletal muscle as an autocrine and paracrine factor.Musclin mRNA is expressed almost exclusively in the skeletal muscle,and is tightly regulated by nutritional status and hormonal factors,especially regulated by insulin.Based on the researches,here is to make a review on musclin structure and distribution,the factors affecting the expression of musclin,at the same time,how musclin play in the lipid metabolismand and glucose metabolism has been a...
