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Potential regulatory mechanisms of lncRNA in diabetes and its complications

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成果类型:
期刊论文
作者:
Feng, Shui-Dong;Yang, Ji-Hua;Yao, Chao Hua;Yang, Si-Si;Zhu, Ze-Mei;...
通讯作者:
Ling, Hong-Yan;Zhang, Liang
作者机构:
[Feng, Shui-Dong] Univ South China, Sch Publ Hlth, Dept Social Med & Hlth Serv Management, Hengyang, Peoples R China.
[Ling, Hong-Yan; Yang, Ji-Hua; Zhu, Ze-Mei; Wu, Di; Yang, Si-Si] Univ South China, Sch Med, Dept Physiol, Hengyang, Peoples R China.
[Zhang, Liang; Yao, Chao Hua] Palmer Ctr Chiropract Res, Lab Cell & Mol Biol, Port Orange, FL 32129 USA.
通讯机构:
[Ling, Hong-Yan] U
[Zhang, Liang] P
Univ South China, Sch Med, Dept Physiol, Hengyang, Peoples R China.
Palmer Ctr Chiropract Res, Lab Cell & Mol Biol, Port Orange, FL 32129 USA.
语种:
英文
关键词:
*complications diabetiques;*diabetes;*diabetic complications;*diabete;*lncRNA;*longs ARNnc
期刊:
BIOCHEMISTRY AND CELL BIOLOGY
ISSN:
0829-8211
年:
2017
卷:
95
期:
3
页码:
361-367
基金类别:
Ministry of Education [[2014]1685]; Science and Technology Department of Hunan Province [2015JC3085]; Key Discipline Construct Program of Hunan province of China (Basic Medicine Sciences in University of South China)
机构署名:
本校为第一且通讯机构
院系归属:
医学院
公共卫生学院
摘要:
Long non-coding RNAs (lncRNAs) are transcripts longer than 200 nucleotides without protein-coding potential. Although these molecules were initially considered as "junk products" of transcription without biological relevance, recent advances in research have shown that lncRNA plays an important role, not only in cellular processes such as proliferation, differentiation, and metabolism, but also in the pathological processes of cancers, diabetes, and neurodegenerative diseases. In this review, we focus on the potential regulatory roles of lncRNA...

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