期刊论文

The Research and Application Progress of Poly (N-isopropylacrylamide) Thermosensitive Hydrogels

中文

高分子通报

1003-3726

2019

2019

7

13-19

10.14028/j.cnki.1003-3726.2019.07.002

湖南省自然科学基金青年基金项目(2018JJ3436) 湖南省教育厅科学研究项目(16C1405) 湖南省大学生研究性学习和创新性实验计划项目(S201910555023) 衡阳市指导性科技计划项目(2017KZ173).

本校为第一机构

温敏水凝胶能够对温度的改变进行响应,在实际应用中备受关注。其中,聚N-异丙基丙烯酰胺（PNIPAM）由于温敏性良好、制备简单、易于修饰等优点,是研究和应用最为广泛的一种温敏水凝胶。近年来,随着研究的进一步深入,特别是化学改性和修饰技术的进步,各种具有优异响应性能的新型PNIPAM温敏水凝胶不断出现,其应用的深度和广度不断扩展和更新,更为贴近实际需求,在生物医药、化学化工等领域前景广阔。本文介绍了PNIPAM温敏水凝胶的温敏性原理及主要的制备方法,重点综述了其在药物释放、细胞支架、传感分析和物质分离等方面的应用现状和发展趋势,对其存在的问题及发展前景进行了分析和展望,为PNIPAM温...

Thermosensitive hydrogels can respond to the change of temperature and attract much attention in practical applications. Among them, poly ( N-isopropylacrylamide)( PNIPAM ) is one of the most widely studied and applied thermosensitive hydrogels because of its good thermosensitivity, simple preparation and easy modification. In recent years, with the further development of research, especially the progress of chemical modification and functionalization technology, a variety of novel PNIPAM thermosensitive hydrogels with excellent response performance have emerged. The depth and breadth of their...