Differentiated Embryo-Chondrocyte Expressed Gene1 and Parkinson’s Disease: New Insights and Therapeutic Perspectives

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Wang, Chun-Yan;Qiu, Zheng-Jie;Zhang, Ping;Tang, Xiao-Qing

通讯作者：

Tang, XQ

作者机构：

[Wang, Chun-Yan; Qiu, Zheng-Jie] Univ South China, Hengyang Med Coll,Key Lab Arteriosclerol Hunan Pr, Hunan Prov Cooperat Innovat Ctr Mol Target New Dr, Hunan Int Sci & Technol Cooperat Base Arterioscle, Hengyang 421001, Hunan, Peoples R China.

[Zhang, Ping] Univ South China, Hengyang Med Sch, Affiliated Nanhua Hosp, Dept Neurol, Hengyang 421001, Hunan, Peoples R China.

[Tang, Xiao-Qing] Univ South China, Hengyang Med Coll, Inst Neurosci, Hengyang Key Lab Neurodegenerat & Cognit Impairme, Hengyang 421001, Hunan, Peoples R China.

[Tang, XQ] Univ South China, Dept Physiol, 28 West Changsheng Rd, Hengyang 421001, Hunan, Peoples R China.

[Tang, XQ] Univ South China, Hengyang Med Sch, Inst Neurosci, 28 West Changsheng Rd, Hengyang 421001, Hunan, Peoples R China.

通讯机构：

[Tang, XQ ] U

Univ South China, Dept Physiol, 28 West Changsheng Rd, Hengyang 421001, Hunan, Peoples R China.

Univ South China, Hengyang Med Sch, Inst Neurosci, 28 West Changsheng Rd, Hengyang 421001, Hunan, Peoples R China.

语种：

英文

关键词：

Central nervous system;DEC1;Neurodegenerative disease;Parkinson's disease;Pathogenesis;Transcription factor

期刊：

CURRENT NEUROPHARMACOLOGY

ISSN：

1570-159X

年：

2023

卷：

期：

页码：

2251-2265

DOI：

10.2174/1570159X21666230502123729

基金类别：

This work was supported by the National Natural Science Foundation of China (82771229), the Natural Science Foundation of Hunan Province (2020JJ4553), and the Hunan Provincial Innovation Foundation for Postgraduate (CX20221003, CX20200962).

机构署名：

本校为第一且通讯机构

院系归属：

医学院

药学与生物科学学院

摘要：

Differentiated embryo-chondrocyte expressed gene1 (DEC1), an important transcription factor with a basic helix-loop-helix domain, is ubiquitously expressed in both human embryonic and adult tissues. DEC1 is involved in neural differentiation and neural maturation in the central nervous system (CNS). Recent studies suggest that DEC1 protects against Parkinson's disease (PD) by regulating apoptosis, oxidative stress, lipid metabolism, immune system, and glucose metabolism disorders. In this review, we summarize the recent progress on the role of DEC1 in the pathogenesis of PD and provide new ins...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Differentiated Embryo-Chondrocyte Expressed Gene1 and Parkinson’s Disease: New Insights and Therapeutic Perspectives

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问