Association of visit-to-visit HbA1c variability with cardiovascular diseases in type 2 diabetes within or outside the target range of HbA1c

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成果类型：

期刊论文

作者：

Sun, Bao;Gao, Yongchao;He, Fazhong;Liu, Zhaoqian;Zhou, Jiecan;...

通讯作者：

Wang, X.;Zhang, W.;Zhou, J.

作者机构：

[Gao, Yongchao; Liu, Zhaoqian; Zhang, Wei; Sun, Bao] Cent South Univ, Xiangya Hosp, Dept Clin Pharmacol, Changsha, Peoples R China.

[Sun, Bao] Cent South Univ, Xiangya Hosp 2, Dept Pharm, Changsha, Peoples R China.

[Sun, Bao] Cent South Univ, Inst Clin Pharm, Changsha, Peoples R China.

[Gao, Yongchao; Liu, Zhaoqian; Zhang, Wei] Cent South Univ, Inst Clin Pharmacol, Hunan Key Lab Pharmacogenet, Changsha, Peoples R China.

[Gao, Yongchao; Liu, Zhaoqian; Zhang, Wei] Minist Educ, Engn Res Ctr Appl Technol Pharmacogen, Changsha, Peoples R China.

通讯机构：

[Zhang, W.] D

[Zhou, J.] T

[Wang, X.] B

Department of Clinical Pharmacology, China

Beijing Hypertension League InstituteChina

语种：

英文

关键词：

HbA1c variability;type 2 diabetes;major microvascular events;within the target range of HbA1c;outside the target range of HbA1c

期刊：

Frontiers in Public Health

ISSN：

2296-2565

年：

2022

卷：

页码：

1052485

DOI：

10.3389/fpubh.2022.1052485

基金类别：

This study was supported by National Scientific Foundation of China (Nos. 82104307, 81573511, 81874329, 82003872, and 81522048), National Key Research and Development Program (Nos. 2016YFC0905000 and 2016YFC0905001), Natural Science Foundation of Hunan Province (Nos. 2021JJ40865 and 2020JJ5513), Scientific Research Fund Project of Hunan Provincial Health Commission (Nos. 20201973 and B202313016776), Scientific Research Fund of Hunan Provincial Education Department (No. 19A418), Central Government Funds for Guiding Local Scientific and Technological Development (2021QZY016), Hunan Province Clinical Medical Technology Innovation Guidance Project (2020SK51823), and Scientific Research Launch Project of the Second Xiangya Hospital of Central South University.

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摘要：

Background: Although a growing attention has been recently paid to the role of HbA1c variability in the risk of diabetic complications, the impact of HbA1c variability on cardiovascular diseases (CVD) in type 2 diabetes is still debated. The aim of the study is to investigate the association of HbA1c variability with CVD in individuals within or outside the target range of HbA1c. Methods: Using data from Action in Diabetes and Vascular disease: preterAx and diamicroN-MR Controlled Evaluation (ADVANCE), we enrolled 855 patients with type 2 diabe...

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Association of visit-to-visit HbA1c variability with cardiovascular diseases in type 2 diabetes within or outside the target range of HbA1c

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