期刊论文

Zhisheng Jiang

英文

Clinica Chimica Acta

0009-8981

2022

534

22-28

10.1016/j.cca.2022.07.004

This article was supported by Project of Health Commission of Hunan Province (202102061771 to Z.R.), National College Students Innovation and Entrepreneurship Training Program (202110555093 to W.-X.X.), College Students Innovation and Entrepreneurship Training Program of University of South China (X2019146 to X.-F.Z.), National Natural Science Foundation of China (81670429, 91839103 to Z.-S.J.), International Joint Laboratory for Arteriosclerotic Disease Research of Hunan Province (2018WK4031), Special Funding for Construction of Innovative Provinces in Hunan Province (2020SK2105 to Z.-S.J.), ‘‘Double First-Class’’ project for innovative Group of Basic Medicine, University of South China (to Z.-S.J.).

本校为第一机构

Atherosclerosis, a chronic inflammatory disease, is a leading cause of death worldwide. Vascular endothelial cells (VECs), vascular smooth muscle cells (VSMCs) and macrophages play extremely vital roles in the formation of atherosclerotic plaques and subsequent atherosclerosis. Necroptosis, a caspase-independent programmed cell necrosis, occurs in advanced atherosclerotic plaques and has been implicated in VEC, VSMC and macrophage function. Although necroptosis may have considered as a defensive line against intracellular infection, it can indu...