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Molecular Epidemiology of Clinical Mycobacterium tuberculosis Isolates from Southern Xinjiang, China Using Spoligotyping and 15-Locus MIRU-VNTR Typing

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成果类型:
期刊论文
作者:
Yin, Chunjie;Mijiti, Xiaokaiti;Liu, Haican;Wang, Quan;Cao, Bin;...
通讯作者:
Li, G.;Xiao, H.
作者机构:
[Xiao, Hui; Yin, Chunjie; Liu, Mengwen] Xinjiang Med Univ, Sch Publ Hlth, Urumqi, Peoples R China.
[Xu, Miao; Mijiti, Xiaokaiti; Wang, Quan] Xinjiang Med Univ, Affiliated Hosp 8, Urumqi, Peoples R China.
[Zhao, Xiuqin; Liu, Haican; Jiang, Yi; Cao, Bin; Li, Machao; Wan, Kanglin; Li, Guilian] Chinese Ctr Dis Control & Prevent, Natl Inst Communicable Dis Control & Prevent, Collaborat Innovat Ctr Diag & Treatment Infect Dis, State Key Lab Infect Dis Prevent & Control, Beijing, Peoples R China.
[Cao, Bin] Univ South China, Sch Publ Hlth, Hengyang, Peoples R China.
[Anwaierjiang, Aiketaguli] Coll Xinjiang Uyghur Med, Hetian, Peoples R China.
通讯机构:
[Li, G.; Xiao, H.] S
State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of China
语种:
英文
关键词:
MIRU-VNTR;spoligotyping;Beijing genotype;drug resistance;genetic diversity;Mycobacterium tuberculosis
期刊:
INFECTION AND DRUG RESISTANCE
ISSN:
1178-6973
年:
2024
卷:
16
页码:
1313-1326
基金类别:
This study was supported by grants from the Major Science and Technology Project of Xinjiang Uygur Autonomous Region (The research and application of key technologies for tuberculosis prevention and treatment in southern Xinjiang, 2017A03006-3) and the Ministry of Science and Technology, China (Mega Projects of Research on the Prevention and Control of HIV/AIDS, Viral Hepatitis Infectious Diseases, 2018ZX10103001-003-012).
机构署名:
本校为其他机构
院系归属:
公共卫生学院
摘要:
Background: In the last decades, the molecular epidemiological investigation of Mycobacterium tuberculosis has significantly increased our understanding of tuberculosis epidemiology. However, few such studies have been done in southern Xinjiang, China. We aimed to clarify the molecular epidemic characteristics and their association with drug resistance in the M. tuberculosis isolates circulating in this area. Methods: A total of 347 isolates obtained from southern Xinjiang, China between Sep, 2017 and Sep, 2019 were included to characterize usi...

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