The intestinal & gamma;& delta;T cells: functions in the gut and in the distant organs

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Li, Guo-Qing;Xia, Jiliang;Zeng, Weihong;Luo, Weijia;Liu, Logen;...

通讯作者：

Cao, DL;Zeng, Xi

作者机构：

[Li, Guo-Qing; Cao, Deliang] Univ South China, Affiliated Hosp 2, Clin Res Ctr, Hengyang Med Sch,Dept Gastroenterol, Hengyang, Hunan, Peoples R China.

[Li, Guo-Qing; Liu, Logen] Univ South China, Affiliated Hosp 2, Hengyang Med Sch, Hunan Prov Key Lab Basic & Clin Pharmacol Res Gast, Hengyang, Peoples R China.

[Luo, Weijia; Zeng, Weihong; Cao, Deliang; Zeng, Xi; Xia, Jiliang] Univ South China, Canc Res Inst, Hengyang Med Sch, Hunan Prov Key Lab Canc Cellular & Mol Pathol, Hengyang, Hunan, Peoples R China.

[Cao, Deliang] Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Dept Oncol, Hengyang, Hunan, Peoples R China.

通讯机构：

[Cao, DL ; Zeng, X] U

Univ South China, Affiliated Hosp 2, Clin Res Ctr, Hengyang Med Sch,Dept Gastroenterol, Hengyang, Hunan, Peoples R China.

Univ South China, Canc Res Inst, Hengyang Med Sch, Hunan Prov Key Lab Canc Cellular & Mol Pathol, Hengyang, Hunan, Peoples R China.

Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Dept Oncol, Hengyang, Hunan, Peoples R China.

语种：

英文

关键词：

mucosal immunity;intestinal & gamma;& delta;T cells;lymphopoiesis;& gamma;& delta;T-epithelial remodeling;and gut & gamma;& delta;T-brain injury repair

期刊：

FRONTIERS IN IMMUNOLOGY

ISSN：

1664-3224

年：

2023

卷：

DOI：

10.3389/fimmu.2023.1206299

基金类别：

Clinical Research Center for Gastric Cancer in Hunan Province [2021SK4029, 2023TP1014]; Key Laboratory for Molecular Diagnosis and Precision Medicine in Hengyang [202010041574]

机构署名：

本校为第一且通讯机构

院系归属：

医学院

摘要：

Located in the frontline against the largest population of microbiota, the intestinal mucosa of mammals has evolved to become an effective immune system. ?d T cells, a unique T cell subpopulation, are rare in circulation blood and lymphoid tissues, but rich in the intestinal mucosa, particularly in the epithelium. Via rapid production of cytokines and growth factors, intestinal ?d T cells are key contributors to epithelial homeostasis and immune surveillance of infection. Intriguingly, recent studies have revealed that the intestinal ?d T cells may play novel exciting functions ranging from ep...

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The intestinal & gamma;& delta;T cells: functions in the gut and in the distant organs

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