National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [11275219, 21201166]; Major Research Plan "Breeding and Trans-mutation of Nuclear Fuel in Advanced Nuclear Fission Energy System" of the Natural Science Foundation of China [91026007]
机构署名:
本校为第一且通讯机构
院系归属:
化学化工学院
摘要:
Interest in bio-toxicology of uranium resulting from its radioactive heavy metal property has been growing enormously in recent years. The interactions between uranium(VI) [U(VI)] and bovine serum albumin (BSA) at physiological pH were studied by spectroscopic methods. Fuorescence results revealed the formation of BSA–U(VI) complex, the binding constants as well as the number of binding sites were determined. In particular, the effects of U(VI) binding on the secondary structures of BSA were examined by means of Fourier transformation infrared...