MC-LR induces and exacerbates Colitis in mice through the JAK1/STAT3 pathway

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Zhou, Xiaodie;Yang, Yue;Yan, Canqun;Feng, Shuidong*;Zhan, Chunhua

通讯作者：

Feng, Shuidong;Zhan, CH;Feng, SD

作者机构：

[Feng, Shuidong; Zhou, Xiaodie; Zhan, Chunhua; Yang, Yue] Univ South China, Sch Publ Hlth, Hunan Prov Key Lab Typical Environmental Pollut &, Hengyang 421001, Peoples R China.

[Yan, Canqun] Univ South China, Affiliated Hosp 2, Hengyang Med Sch, Sch Publ Hlth, Hengyang, Peoples R China.

[Zhan, Chunhua] Cent Hosp Shaoyang, Dept Publ Hlth, Shaoyang, Peoples R China.

[Feng, Shuidong] Univ South China, Sch Publ Hlth, Hengyang Med Sch, Hengyang, Hunan, Peoples R China.

通讯机构：

[Feng, SD; Zhan, CH ; Feng, SD ] U

Univ South China, Sch Publ Hlth, Hunan Prov Key Lab Typical Environmental Pollut &, Hengyang 421001, Peoples R China.

Univ South China, Sch Publ Hlth, Hengyang Med Sch, Hengyang, Hunan, Peoples R China.

语种：

英文

关键词：

Microcystin-LR;Colitis;Inflammatory bowel disease;JAK1;STAT3

期刊：

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

ISSN：

1528-7394

年：

2025

卷：

期：

页码：

373-383

DOI：

10.1080/15287394.2024.2443227

基金类别：

Health Research Project of Hunan Provincial Health Commission [202203064882]; Hunan Provincial Natural Science Fund [2018JJ2342]; Hunan Provincial Natural Science Youth Fund [2024JJ6392]

机构署名：

本校为第一且通讯机构

院系归属：

公共卫生学院

摘要：

Inflammatory bowel disease (IBD) is a complex gastrointestinal disorder attributed to genetic and environmental factors. Microcystin-leucine-arginine (MC-LR) is an environmental toxin that accumulates in the gut and produces intestinal damage. The aim of this study was to investigate the effects of exposure to MC-LR on development and progression of IBD as well examine the underlying mechanisms of microcystin-initiated tissue damage. Male C57BL/6 mice were treated with either MC-LR alone or concurrently with dextran-sulfate sodium (DSS). Mice w...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

MC-LR induces and exacerbates Colitis in mice through the JAK1/STAT3 pathway

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问