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Effect of vitamin D supplementation on pancreatic β-cell destruction and type 1 diabetes

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成果类型:
期刊论文
作者:
Hu Xiao-Bo;Duan Ting-Ting;Liu Jun;Zhu Gao-Lu;Cao Zhao-Hui;...
作者机构:
[Shao-Long Feng] The Institute of Preventive Medicine, School of Public Health, Guilin Medical University, Guilin, Guangxi 541004, China.
[Ting-Ting Duan; Gao-Lu Zhu] The Key Laboratory of Ecological Environment and Critical Human Diseases Prevention, Education Department of Hunan Province, Department of Biochemistry, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China
The Key Laboratory of Typical Environmental Pollution and Health Hazards, Hunan Province, University of South China, Hengyang, Hunan 421001, China
[Xiao-Bo Hu; Jun Liu; Zhao-Hui Cao] The Key Laboratory of Ecological Environment and Critical Human Diseases Prevention, Education Department of Hunan Province, Department of Biochemistry, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China<&wdkj&>The Key Laboratory of Typical Environmental Pollution and Health Hazards, Hunan Province, University of South China, Hengyang, Hunan 421001, China
语种:
英文
期刊:
中华医学杂志(英文版)
ISSN:
0366-6999
年:
2021
卷:
134
期:
1
页码:
41-43
基金类别:
Natural Science Foundation of China(No. 41877390); the Nature Science Fund of Hunan Province(No. 2019JJ40240, 2016JJ2113); Education and Innovation Fund of University of South China(No. 2019JG029);
机构署名:
本校为第一且通讯机构
院系归属:
药学与生物科学学院
摘要:
Type 1 diabetes (T1D) is an organ-specific autoimmune disease with loss of pancreatic β-cells, characterized by reduced insulin levels and increased blood glucose. The incidence of T1D is increasing by approximately 2% to 5% worldwide every year and becoming a global health problem. Vitamin D (VD) deficiency was reported to be a risk factor in the development of T1D. Recent studies showed that supplementation of VD alleviated disease symptoms in T1D patients. However, a few randomized controled trials (RCTs) demonstrated the clinical effect of...

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