Endoplasmic reticulum stress（ERS） induced by various types of stress with endoplasmic reticulum dysfunction, which leads to the accumulation of misfolded and unfolded proteins and the disturbance of cells homeostasis, is a series of regulatory response the stressed cell restores normal function. ERS is a double-edged sword of triggering cell adaptive survival, apoptosis or autophagy, extensively involving the pathogenesis of many diseases. The lung cell apoptosis is the important mechanism of COPD. The present study indicate ERS pl...
