期刊论文

Progress on immunological characteristics and combined immunization of DNA vaccine and protein vaccine

中文

国际免疫学杂志

1673-4394

2010

33

2

89-91,96

10.3760/cma.j.issn.1673-4394.2010.02.003

国家自然科学基金资助项目（30771931）

本校为第一机构

核酸疫苗和蛋白疫苗具有各自的免疫特点,分别诱导以细胞免疫和体液免疫为主的免疫应答,并能通过联合免疫提高机体预防病原体的免疫保护力,而核酸疫苗和蛋白疫苗的免疫特点以及联合使用核酸疫苗与蛋白疫苗协同免疫可以提高疫苗免疫效果.

DNA vaccine and protein vaccine have their own immunological characteristics. DNA vaccine mainly induces cellullar immunologic responses and protein vaccine mainly induces humoral immunological response. So DNA vaccine and protein vaccine can improve the protection against pathogens by combined immunization. This article summarizes the immunological characteristics of DNA vaccine and protein vaccine and the progress of research on using DNA prime-pr...