Mucosal immunity can effectively induce both mucosal and systemic immune responses to protect mucosa against pathogens. In general, vaccines alone are not sufficiently taken up after mucosal administration and result in poor immune responses. Therefore, adjuvant/delivery systems are required to enhance the immune response. Chitosan is a natural polymer which exerts advantages as a adjuvant or vaccine carrier due to its bioadhesive properties and immune-modulating activity. This review article focuses on mucosal immunizati...