期刊论文

Zheng, Zi-Tong

英文

Archiv der Pharmazie

0365-6233

2020

353

7

2000044-

10.1002/ardp.202000044

The authors thank the Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (2018‐10), the general project of the University of South China (18C0438), Hunan Graduate Science and Technology Innovation Projects (CX2018B585), the Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study (0223‐0007‐000004), the Undergraduate Research Learning and Innovative Experiment Project, University of South China (2019‐100, 2018XJXZ188, 2018XJXZ350, 2018XJXZ194, 2018XJXZ351), the Guiding Project of Hengyang Science and Technology Department (S2018F9031015299), Program for Innovative Talent Team of Hengyang (2017‐1), the Key Project of Hengyang Science and Technology Department (2017KJ166) for financial support.

本校为第一且通讯机构

Resveratrol is a natural phytoestrogen produced by plants to protect themselves from injury, UV irradiation, and fungal attack. The main active structure is E-resveratrol, which has many pharmacological activities. As the structure of resveratrol is similar to the natural estrogen 17β-estradiol and the synthetic estrogen E-diethylstilbestrol, resveratrol is used in reducing the incidence of breast cancer. However, the therapeutic application of resveratrol is limited due to its low bioavailability. To improve its bioavailability and pharmacolo...