期刊论文

Xiao, ZJ

英文

International Immunopharmacology

1567-5769

2023

117

109614

10.1016/j.intimp.2022.109614

Guijuan Zhou: Conceptualization, Methodology, Software, Data curation, Writing – original draft, Software, Validation, Writing – review & editing. Qing Ye: Data curation, Writing – original draft, Software, Validation. Yan Xu: Data curation, Writing – original draft, Visualization, Investigation. Bing He: Data curation, Writing – original draft, Visualization, Investigation, Writing – review & editing. Lin Wu: Data curation, Writing – original draft, Visualization, Investigation. Guanghua Zhu:

本校为第一且通讯机构

Cerebral amyloid angiopathy (CAA) is characterized by the cerebrovascular amyloid-β (Aβ) accumulation, and always accompanied by Alzheimer's disease (AD). Mitochondrial dysfunction-associated cellular events including cell death, inflammation and oxidative stress are implicated in the progression of CAA. Unfortunately, the molecular mechanisms revealing CAA pathogenesis are still obscure, thus requiring further studies. Mitochondrial calcium uptake 3 (MICU3), a regulator of the mitochondrial Ca(2+) uniporter (MCU), mediates various biological...